Moore's memoir, Inside Out, was published on September 24, 2019 by HarperCollins. On October 13, 2019, the book debuted at number one on The New York Times' Combined Print & E-Book Nonfiction best-sellers list and the Hardcover Nonfiction best-sellers list. Moore discussed the book in an exclusive interview with Diane Sawyer of ABC News on Good Morning America. Moore and her two daughters Rumer and Tallulah appeared on Jada Pinkett Smith's web television talk show Red Table Talk on November 4, 2019.
In her next film, the drama Blind (2017), Moore starred opposite Alec Baldwin, portraying the neglected wife of an indicted businessman having an affair with a novelist blinded in a car crash. In February 2017, Moore joined the cast of Empire, in the recurring role of a take-charge nurse with a mysterious past. The comedy film Rough Night (2017) featured Moore as one half of a nymphomaniac couple seducing a member of a bachelorette party gone wrong. The film was released in the United States on June 16, 2017, by Columbia Pictures, received mixed reviews and grossed $47 million worldwide. She played Selma in the Indian drama film Love Sonia (2018), which tells the story of a young girl's journey to rescue her sister from the dangerous world of international sex trafficking. She portrayed Lucy, a superficial CEO in the comedy horror film Corporate Animals (2019), which premiered at the Sundance Film Festival on January 29, 2019.
More InfoMoore starred in the thriller The Juror (1996). It was a box office bomb and was heavily panned by critics. Moore produced and starred in a controversial miniseries for HBO called If These Walls Could Talk (1996), a three-part anthology about abortion alongside Sissy Spacek and Cher. Its screenwriter, Nancy Savoca, directed two segments, including one in which Moore played a widowed nurse in the early 1950s seeking a back-alley abortion. For that role, Moore received a second Golden Globe nomination as Best Actress. Also in 1996, she provided the speaking voice of the beautiful Esmeralda in Disney's animated adaptation of The Hunchback of Notre Dame, and starred in Mike Judge's comedy Beavis and Butt-head Do America, alongside her then husband Bruce Willis.
More InfoMoore's film career took off in 1984 following her appearance in the sex comedy Blame It on Rio. She portrayed Laura Victor in the comedy film No Small Affair (1984), opposite Jon Cryer. Her commercial breakthrough came in Joel Schumacher's yuppie drama St. Elmo's Fire (1985), which received negative reviews, but was a box office success and brought Moore to international recognition. Because of her association with that film, Moore was often listed as part of the Brat Pack, a label she felt was "demeaning". She progressed to more serious material with About Last Night... (1986), co-starring Rob Lowe, which marked a positive turning point in her career, as Moore noted that, following its release, she began seeing better scripts. Film critic Roger Ebert gave the film four out of four stars and praised her performance, writing, "There isn't a romantic note she isn't required to play in this movie, and she plays them all flawlessly." The success of About Last Night... was unrivaled by Moore's other two 1986 releases, One Crazy Summer and Wisdom, the last youth-oriented films in which she would star. She was listed as one of twelve "Promising New Actors of 1986" in John Willis's Screen World, Vol. 38.
More InfoMoore was off screen for three years before re-emerging in the arthouse psychological drama Passion of Mind (2000), the first English-language film from Belgian director Alain Berliner. Her performance as a woman with multiple personality disorder was well received, but the film itself garnered mixed reviews and was deemed "naggingly slow" by some critics. Moore then resumed her self-imposed career hiatus and continued to turn down film offers. Producer Irwin Winkler said in 2001, "I had a project about a year and a half ago, and we made an inquiry about her—a real good commercial picture. She wasn't interested."
More InfoMoore made her film debut with a brief role in the 1981 teen drama Choices, directed by Silvio Narizzano. Her second film feature was the 3-D sci-fi horror film Parasite (1982), for which director Charles Band had instructed casting director Johanna Ray to "find me the next Karen Allen." Moore then joined the cast of the ABC soap opera General Hospital, playing the role of an investigative reporter until 1983. During her tenure on the series, she made an uncredited cameo appearance in the 1982 spoof film Young Doctors in Love.
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